Depression is one of the greatest problems and killers of our time. Here we list the latest depression statistics, reveal surprising facts about underlying depression causes, the failure of standard treatments, and what works for depression in the long-term.
Depressive disorders affect approximately 18.8 million American adults or about 9.5% of the U.S. population age 18 and older in a given year. This includes major depressive disorder, dysthymic disorder, and bipolar disorder. [1]
Everyone, will at some time in their life be affected by depression -- their own or someone else's, according to Australian Government statistics. (Depression statistics in Australia are comparable to those of the US and UK.) [2]
Pre-schoolers are the fastest-growing market for antidepressants. At least four percent of preschoolers -- over a million -- are clinically depressed. [3]
Depression will be the second largest killer after heart disease by 2020 -- and studies show depression is a contributory factor to fatal coronary disease. [12]
Depression results in more absenteeism than almost any other physical disorder and costs employers more than US$51 billion per year in absenteeism and lost productivity, not including high medical and pharmaceutical bills. [13]
Antidepressants work for 35 to 45% of the depressed population, while more recent figures suggest as low as 30%. [14]
Standard antipressants, SSRIs such as Prozac, Paxil (Aropax) and Zoloft, have recently been revealed to have serious risks, and are linked to suicide, violence, psychosis, abnormal bleeding and brain tumors. [15]
Government (FDA) warnings highlight concerns over the efficacy and use of antidepressants in children. Antidepressants with the exception of Prozac have been banned in Britain for children. The BMJ recently reported they found no scientific evidence whatsoever that SSRIs work for preschoolers (or for anyone under eighteen). [16]
Antidepressants (particularly SSRIs) work only as well (or less) than placebos. [17]
Short-term (exogenous) depression can be caused by loss or extreme trauma.
Chronic or life-long (endogenous) depression is caused by trauma in childhood which includes: emotional, physical or sexual abuse; yelling or threats of abuse; neglect (even two parents working); criticism; inappropriate or unclear expectations; maternal separation; conflict in the family; divorce; family addiction; violence in the family, neighborhood or TV; racism and poverty. [19]
Certain neurochemicals are also involved, such as a surplus of noradrenaline, perhaps as a result of the structural problem. Recent studies indicate that serotonin, which is targeted by most antidepressants (SSRIs), is not as much a factor in depression as the long-term presence of stress hormone cortisol. [21]
Physiological problems, plus learned beliefs and behaviors, make functional decisions difficult, and the results reinforce the depression in a vicious cycle.
Studies are increasingly linking more illnesses to depression, including: osteoporosis, diabetes, heart disease, some forms of cancer, eye disease and back pain. [24]
We believe that long-term recovery from depression ultimately requires addressing the underlying relationship causes of depression, not simply symptoms such as chemical imbalance and depressive thoughts. This is why healing both the relationship environment and the whole person is vital in preventing relapse. (The Uplift Program has a 94% success rate, according to follow-up questionnaires up to 2 years later.)
Good relationships: studies show that relationships with partners, carers, teachers, co-workers and a supportive social network results in physical and emotional healing, happiness and life satisfaction, and prevents isolation and loneliness, major factors in depressive illness. [25]
Techniques to boost self-esteem and a sense of competence.
Feldenkrais or Repatterning Movements (RPMs) that promote immediate improvements in wellbeing and effective movement while stimulating the brain to learn to form new connections on the basis of function instead of habit. [28]
Moderate and even gentle exercise such as a brief walk. [29] Feldenkrais-type movements also help ease chronic pain often associated with depression and enable people to learn more functional, efficient and pleasurable ways of walking.
[2] Australian Institute of Health and Welfare, 1998. “National Health Priority Areas Mental Health: A Report Focusing on Depression.” Depression statistics in Australia are comparable to those of the US and UK.
[10] D F Bailey, and J L Moore, III. “Emotional Isolation, Depression, and Suicide Among African American Men: Reasons for Concern.” In C Rubin (Ed), Linking Lives Across Borders: Gender-Sensitive Practice in International Perspective, (Pacific Grove, CA Books/Cole).
[11] Agency for Healthcare Research and Quality, 2003. “National Healthcare Quality Report.” This is a widely quoted statistic, though some experts such as Dr Christopher L Summerville, Executive Director of the Manitoba Schizophrenia Society, member of the Board of Directors of Mood Disorders of Canada, have cited higher figures.
[14] Newer figures are lower but this figure was reported in the NY Times article Antidepressants Lift Clouds, But Lose 'Miracle Drug' Label, June 30, 2002. Also C Bruce Baker, MD, “Quantitative Analysis of Sponsorship Bias in Economic Studies of Antidepressants,” The British Journal of Psychiatry 2003, 183: 498-506.
[15] S. Vedantam. “FDA Links Antidepressants, Youth Suicide Risk.” Washington Post, 23 February, 2004, page A01. W. Meijer, et al. “Association of Risk of Abnormal Bleeding with Degree of Serotonin Reuptake Inhibition by Antidepressants,” Archives of Internal Medicine 2004, 164:2367-2370. Health news story: Antidepressants May Increase Risk of Abnormal Bleeding.
[18] Jackie Gollan, University of Washington, report presented to the Association For the Advancement of Behavior Therapy, December 1999.
[19] Virtually every recent study has linked depression to childhood trauma and abuse including Deborah Lott, “Childhood Trauma, CRF Hypersecretion and Depression,” Psychiatric Times, October 1999, 16:(10); Danya Glaser, “Child Abuse and Neglect and the Brain,” J Child Psychol. & Psychiat. 2000, 41:1:97-116; L Rowell Huesmann, et al., University of Michigan, “Longitudinal Relations Between Children's Exposure to TV Violence and Their Aggressive and Violent Behavior in Young Adulthood: 1977 - 1992,” Developmental Psychology, 39:2. An up-to-date definition of what constitutes childhood abuse can be found in the American Academy of Pediatrics report, “The Psychological Maltreatment of Children,” April 2, 2002. Health news stories: Stress and Trauma Increase Risk of Depressive and Anxiety Disorders, Maternal Deprivation Triggers Manic Depression.
[20] Studies include Meena Vythilingam, “Childhood Trauma Associated With Smaller Hippocampal Volume in Women With Major Depression,” American Journal of Psychiatry, 2002, 159:2072-2080, see Smaller Hippocampal Volume Predicts Vulnerability to Psychological Trauma. J D Connolly et al., “Human fMRI Evidence for the Neural Correlates of Preparatory Set,” Nature Neuroscience, 2002, 5:1345-1352. Also Daniel Amen, MD, “Why Don't Psychiatrists Look at the Brain,” Neuropsychiatry Review, February 2001, 2:1.
[22] Widely known, but see Prof Steven Dubovsky, Mind Body Deceptions (New York, Norton & Co, 1997).
[23] J I Escobar et al, “Somatization in the Community,” Archives of General Psychiatry (1987) 44:713-718; and Z J Lipowski, “Somatization: Medicine's Unsolved Problem,” Psychosomatics, 1987, 28:294-297. More recent studies have come to the same broad conclusions. See A J Barsky, “Somatization and Medicalization in the Era of Managed Care,” Journal of the American Medical Association (JAMA), 1995, 274:1931-1934. Health news stories: Depression Lowers Immunity, Depression and Illness
[25] Numerous studies support our assertion that good relationships are the most important healing mechanism in mood disorders. See Roy F Baumeister, and Mark R Leary, “The Need to Belong: Desire for Interpersonal Attachments as a Fundamental Human Motivation,” Psychological Bulletin, 1995, 117(3)497-529. Press release: Caring Relationships Crucial to Healing. For relationships as factors in happiness and life satisfaction see our health news stories If Richer Isn't Happier, What Is?, Happiness Is....
[26] See T Stompe et al., “Guilt and Depression: A Cross-Cultural Comparative Study,” Psychopathology, 2001, 34(6):289-98.
[28] Alicia Fortinberry has applied the work of Moshe Feldenkrais to develop Repatterning Movements (RPMs), which address emotional patterns and help heal depression.
[29] For example J Blumenthal et al., "Effects of Exercise Training on Older Patients With Major Depression," Archives of Internal Medicine 1999, 159:2349-2356. In a follow-up study carried out 6 months later the team found that walkers relapsed far less than those only on antidepressants. Health news stories: Better Mood a Short Walk Away, Why Exercise Cheers You Up.
Dr Bob Murray is a widely published psychologist and expert on emotional health and optimal relationships. Alicia Fortinberry is a psychotherapist, health writer and executive coach. Together they are the founders of the highly successful Uplift Program, and authors of Raising an Optimistic Child (McGraw-Hill, 2006) and Creating Optimism (McGraw-Hill, 2004).
Disclaimer: The diagnosis and treatment of medical or psychiatric disorders requires trained professionals. The information provided in this article is for educational purposes only. It should NOT be used as a substitute for seeking professional help.
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Disclaimer: The information presented on this website is based on the research, clinical experience and opinions of Dr Bob Murray and Alicia Fortinberry. It is designed to support, not replace a relationship with a qualified healthcare professional.